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Table. 3.

Table. 3.

Adjusted odds ratios and 95% confidence intervals from multiple logistic regression analysis of GI medication prescription

Explanatory variables Patients without underlying GI disorders in the previous 6 months excluding the date of diagnosis of acute cystitis (Group A) Patients without underlying GI disorders in the previous 6 months including the date of diagnosis of acute cystitis (Group B)

Adj. OR 95% p-value Adj. OR 95% p-value
Age 20-29 (R)
30-39 0.880 0.590-1.312 0.531 1.160 0.626-2.154 0.636
40-49 0.927 0.632-1.353 0.693 1.200 0.684-2.116 0.526
50-64 0.848 0.580-1.235 0.392 1.346 0.775-2.353 0.293
65-74 0.686 0.377-1.269 0.222 0.780 0.285-2.035 0.617
≥75 0.372 0.172-0.184 0.012 0.163 0.022-0.733 0.334
Insurance type NHI (R)
MedAid/PVI 0.895 0.330-2.864 0.837 1.045 0.132-6.244 0.962
Comorbidity Hypertension No (R)
Yes 1.511 0.946-2.465 0.092 1.729 0.880-3.449 0.114
Diabetes mellitus No (R)
Yes 0.894 0.534-1.534 0.572 1.030 0.463-2.248 0.941
Myocardial Infarction & Cardiovascular Disease No (R)
Yes 2.791 0.874-12.488 0.148 2.517 0.498-13.153 0.255
An inflammatory disease of the female pelvic organs No (R)
Yes 0.727 0.502-1.064 0.060 1.213 0.779-1.889 0.392
Non-inflammatory disorders in the female reproductive tract No (R)
Yes 1.297 0.833-2.068 0.298 1.096 0.623-1.923 0.749
Class of oral antibiotics Penicillins (R)
1st Gen Cephalosporines 0.605 0.349-1.049 0.072 0.550 0.226-1.306 0.180
2nd Gen Cephalosporines 1.012 0.658-1.529 0.956 1.031 0.552-1.936 0.922
3rd Gen Cephalosporines 0.361 0.157-0.850 0.017 0.218 0.031-0.976 0.007
Quinolones 0.812 0.524-1.239 0.341 0.794 0.417-1.519 0.483
Sulfonamides 0.281 0.153-0.510 <0.001 0.327 0.123-0.812 0.019
Others * 0.810 0.425-1.585 0.529 1.279 0.519-3.191 0.593
Parenteral antibiotic use No (R)
Yes 1.162 0.904-1.494 0.241 1.399 0.961-2.042 0.110
Region Seoul (R)
Gyeonggi, Gangwon 0.808 0.588-1.107 0.186 0.941 0.577-1.538 0.806
Gyeonsang 1.303 0.906-1.880 0.154 2.216 1.309-3.789 0.003
Jeolla, Jeju 1.117 0.683-1.869 0.666 2.200 1.014-4.933 0.047
Chungcheong, Sejong 0.745 0.483-1.159 0.186 0.822 0.410-1.622 0.575
Physician specialties General (R)
Internal medicine 0.904 0.609-1.347 0.619 0.886 0.445-1.737 0.726
Obstetrics & Gynecology 1.198 0.862-1.659 0.279 1.642 0.999-2.724 0.052
Urology 2.056 1.356-3.151 <0.001 2.061 1.097-3.904 0.025
Family medicine 0.799 0.439-1.492 0.470 1.692 0.729-3.909 0.217
Others* 2.248 0.991-5.814 0.068 1.933 0.596-6.378 0.269

*Others include orthopedic surgery, neurosurgery, chest surgery, plastic surgery, otolaryngology, neurology, psychology, anesthetics, ophthalmology, clinical pathology, rehabilitation medicine, pediatric

Abbreviation: Gen, generation; GI, gastrointestinal; MedAid, Medical Aid; NHI, National Health Insurance; PVI, Patriots & Veterans Insurance; R, reference

Korean J Clin Pharm 2023;33:8-21 https://doi.org/10.24304/kjcp.2023.33.1.8
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