pISSN 1226-6051
eISSN 2508-786X
eISSN 2508-786X
Serious adverse events(SAE) reports of calcineurin inhibitors from 2017 to 2021
| Serious adverse events (SAE) | Total, n (%) | Cyclosporine, n (%) | Tacrolimus, n (%) |
|---|---|---|---|
| Congenital anomaly | 19 (0.1) | 2 (0.0) | 17 (0.1) |
| Death | 3,426 (10.9) | 880 (12.8) | 2,546 (10.3) |
| Disability | 179 (0.6) | 65 (1.0) | 114 (0.5) |
| Hospitalization | 7,979 (25.3) | 1,314 (19.1) | 6,665 (27.1) |
| Life-threatening | 1,252 (4.0) | 207 (3.0) | 1,045 (4.3) |
| Required intervention to prevent permanent impairment/damage | 19 (0.1) | 7 (0.1) | 12 (0.1) |
| Others | 13,949 (44.3) | 3,241 (47.2) | 10,708 (43.5) |
| Unknown | 4,659 (14.8) | 1,153 (16.8) | 3,506 (14.2) |