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Table. 1.

Table. 1.

Demographic characteristics and frequency of prescribing contraindicated drug combinations

Explanatory variables n (%) Prescribing contraindicated drug combinations P-value
Overall 49773 (100.0) 163 (0.3)
Sex 0.055
Male 17794 (35.8) 70 (0.4)
Female 31979 (64.3) 93 (0.3)
Age(Years) < 0.001
20-39 9405 (18.9) 13 (0.1)
40-54 9090 (18.3) 11 (0.1)
55-64 8934 (17.9) 35 (0.4)
65-74 9214 (18.5) 52 (0.6)
≥75 13130 (26.4) 52 (0.4)
Insurance type 0.447
NHI 44264 (88.9) 148 (0.3)
Non-NHI 5509 (11.1) 15 (0.3)
Main disease < 0.001
Mental disorder 47704 (95.8) 24 (0.1)
Parkinson 1418 (2.8) 99 (7.0)
Both 651 (1.3) 40 (6.1)
Physician specialty < 0.001
General practitioner 9164 (18.4) 17 (0.2)
Neurologist 5025 (10.1) 85 (1.7)
Orthopedist 3898 (7.8) 21 (0.5)
Psychiatrist 6809 (13.7) 18 (0.3)
Internist 11852 (23.8) 6 (0.1)
Others 13025 (26.2) 16 (0.1)
Region 0.361
Capital 23188 (46.6) 85 (0.4)
Metropolitan 10428 (21.0) 31 (0.3)
Rural 16157 (32.5) 47 (0.3)
Institution < 0.001
Tertiary 3122 (6.3) 35 (1.1)
Secondary 6232 (12.5) 55 (0.9)
Primary 40419 (81.2) 73 (0.2)
Comorbidities
Hypertension 22265 (44.7) 91 (0.4) 0.004
Diabetes mellitus 14581 (29.3) 60 (0.4) 0.035
Hyperlipidemia 26286 (52.8) 107 (0.4) 0.001
Osteoarthritis 19964 (40.1) 82 (0.4) 0.008
Rheumatic arthritis 2477 (5.0) 15 (0.6) 0.013
DUR contraindication < 0.001
No 49668 (99.8) 58 (0.1)
Yes 105 (0.2) 105 (100.0)

NHI, National health insurance; DUR, Drug Utilization Review.

Korean J Clin Pharm 2022;32:313-20 https://doi.org/10.24304/kjcp.2022.32.4.313
© 2022 Korean J Clin Pharm