pISSN 1226-6051
eISSN 2508-786X
eISSN 2508-786X
Definition and signal detection criteria of implemented data mining indicesM24,25)
Indices | Definition | Criteria for signal detection |
---|---|---|
PRR (Proportional Reporting Ratio) | P(AE,Drug)/ P(AE,-Drug) | Adverse events≥3, PRR≥2, Chi-squared≥4 |
ROR (Reporting Odds Ratio) | Adverse events≥3, ROR≥2, Chi-squared≥4 | |
IC (Information Component) | log2 P(AE,Drug)/P(AE)P(Drug) | Lower limit of 95% CI > 0 |
* - AE: One specific adverse event didn’t represent, -Drug: One specific drugs didn’t administered