Korean Journal of Clinical Pharmacy

Table. 1. Table 1

Definition and signal detection criteria of implemented data mining indicesM^24,25)

Indices	Definition	Criteria for signal detection
PRR (Proportional Reporting Ratio)	P(AE,Drug)/ P(AE,-Drug)	Adverse events≥3, PRR≥2, Chi-squared≥4
ROR (Reporting Odds Ratio)	PAE, Drug / P−AE, DrugP−AE, Drug/ PAE, −Drug	Adverse events≥3, ROR≥2, Chi-squared≥4
IC (Information Component)	log₂ P(AE,Drug)/P(AE)P(Drug)	Lower limit of 95% CI > 0

* - AE: One specific adverse event didn’t represent, -Drug: One specific drugs didn’t administered