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Table. 2.

Table. 2.

Comparison of PBPK, lumping model and 2-compartment model for pharmacokinetic parameters of voriconazole

PK parameter PBPK model Lumping model 2-Compartment model
CL (L/hr/kg) 0.106 0.106 0.088
Vc (L/kg) 1.005 1.005 1.129
Vp (L/kg) 1.033 5.173 1.471

CL, clearance; Vc, central volume of distribution; Vp, peripheral volume of distribution

Korean J Clin Pharm 2021;31:125-35 https://doi.org/10.24304/kjcp.2021.31.2.125
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