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Table. 3.

Table. 3.

Comparison of changes in renal function and renal replacement therapy between two groups

Classifications Tacrolimus group (n=61) Basiliximab group (n=24) p value
SCr after AKI, mg/dL, median (IQR)
SCr day 0 0.58 (0.45-0.81) 1.36 (0.97-1.94) <0.001*
SCr day 14 0.55 (0.46-0.70) 0.73 (0.50-1.36) 0.008*
∆SCr -0.02 (-0.13-0.09) -0.39 (-0.93--0.02) <0.001*
RRT after AKI, n (%) 5 (8.2) 19 (79.2) <0.001
CRRT 3 (4.9) 7 (29.2)
HD 0 (0) 1 (4.2)
CRRT and HD 2 (3.3) 11 (45.8)
Renal function tests after LT, median (IQR)
BUN, mg/dl
∆3 months 9.10 (3.59-15.58) 12.10 (1.07-25.32) 0.179*
∆6 months 8.90 (4.80-14.77) 11.25 (5.03-19.65) 0.134*
∆12 months 8.30 (3.26-12.53) 9.20 (4.41-15.62) 0.353*
SCr, mg/dl
∆3 months 0.17 (0.03-0.29) 0.19 (-0.09-1.05) 0.224*
∆6 months 0.21 (0.01-0.32) 0.15 (-0.03-0.66) 0.490*
∆12 months 0.28 (0.13-0.45) 0.29 (-0.03-0.94) 0.376*

* Mann-Whitney U test

Fisher’s exact test

SCr day 0 and SCr day 14 included serum creatinine levels on day 0 and day 14 after AKI development, respectively.

AKI; Acute kidney injury, BUN; Blood urea nitrogen, CRRT; Continuous renal replacement therapy, HD; hemodialysis, IQR; Interquartile range, LT; ion, RRT; Renal replacement therapy, SCr; Serum creatinine

Korean J Clin Pharm 2020;30:149-60 https://doi.org/10.24304/kjcp.2020.30.3.149
© 2020 Korean J Clin Pharm