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Table. 3.

Table. 3.

Univariable analysis comparison between normal elimination group and delayed elimination group

Normal (N=62)Delayed (N=23)p-value
Age (year)9.94 ± 5.5511.78 ± 4.540.157
BMIa (kg/m2)29.23 ± 5.2330.65 ± 5.250.271
SCrb (mg/dL)0.39 ± 0.160.45 ± 0.150.126
CrClc (mL/min/1.73 m2)221.60 ± 57.10217.60 ± 57.700.775
BUNd (mg/dL)8.81 ± 3.128.35 ± 3.690.575
ASTe (IU/L)52.39 ± 50.8361.78 ± 64.160.659
ALTf (IU/L)57.71 ± 79.961.78 ± 64.160.827
Albumin (g/dL)4.15 ± 0.514.13 ± 0.470.866
Prehydration (hour)19.08 ± 8.9021.52 ± 11.890.310
Number of high dose MTXg cycles, n2 (1-4)2 (1-4)0.131
Drugs, n (%)None24 (38.7)5 (21.7)0.143
Furosemide34 (54.8)17 (73.9)0.111
PPIh12 (19.4)3 (13.0)0.750
NSAIDi0 (0.0)1 (4.3)0.271
Aminoglycoside0 (0.0)2 (8.7)0.071

*Mean ± standard deviation or Median (range)

Body mass index

Serum creatinine

Creatinine clearance

Blood urea nitrogen

Aspartate aminotransferase

Alanine aminotransferase

Methotrexate

Proton-pump inhibitor

Nonsteroidal anti-inflammatory drug

Korean J Clin Pharm 2019;29:101-8 https://doi.org/10.24304/kjcp.2019.29.2.101
© 2019 Korean J Clin Pharm