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Table. 3.

Table. 3.

Antibiotics use between therapeutic drug monitoring (TDM) and non-TDM groups

TDM (n = 27)non-TDM (n = 27)Total (n = 54)p-value
Penicillins, N(%)4 (14.8)3 (11.1)7 (13.0)1.000
Pip/Tazo, N(%)14 (51.9)10 (37.0)24 (44.4)0.273
Cephalosporins, N(%)
 2ndgeneration1 (3.7)2 (7.4)3 (5.6)1.000
 3rd generation19 (70.4)14 (51.9)33 (61.1)0.163
 4th generation11 (40.7)8 (29.6)19 (35.2)0.393
Carbapenems, N(%)21 (77.8)19 (70.4)40 (74.1)0.535
Fluoroquinolones, N(%)25 (92.6)20 (74.1)45 (83.3)0.142
Aminoglycosides, N(%)17 (63.0)11 (40.7)28 (51.9)0.102
Macrolides, N(%)9 (33.3)7 (25.9)16 (29.6)0.551
Tetracyclines, N(%)2 (7.4)1 (3.7)3 (5.6)1.000
Glycopeptides, N(%)21 (77.8)18 (66.7)39 (72.2)0.362
Oxazolidinones, N(%)5 (18.5)2 (7.4)7 (13.0)0.420
Polymyxins, N(%)14 (51.9)8 (29.6)22 (40.7)0.097
Metronidazole, N(%)10 (37.0)6 (22.2)16 (29.6)0.233
TMP/SMX, N(%)26 (96.3)23 (85.2)49 (90.7)0.159

Data are the No. (%)

From the Chi-square test or Fisher’s exact test

Pip/Tazo, piperacillin/tazobactam; TMP/SMX, trimethoprim/sulfamethoxazole

Korean J Clin Pharm 2019;29:89-100 https://doi.org/10.24304/kjcp.2019.29.2.89
© 2019 Korean J Clin Pharm