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Table. 2.

Table. 2.

Baseline patient characteristics

TDM (n = 27)non-TDM (n = 27)Total (n = 54)p-value
Age, years55.1 ± 11.155.3 ± 11.255.2 ± 10.90.800a

Gender
 Male, N(%)16 (59.3)18 (66.7)34 (63.0)0.573b
 Female, N(%)11 (40.7)9 (33.3)20 (37.0)
Height, cm165.3 ± 8.0164.9 ± 7.1165.1 ± 7.40.540a
Weight, kg53.8 ± 11.552.3 ± 10.653.1 ± 10.90.870a
BMI, kg/m219.6 ± 3.619.2 ± 3.619.4 ± 3.50.830a

Immunosuppressive drug
 Triple regimenc21 (77.8)19 (70.4)40 (74.1)0.535b
 Double regimend2 (7.4)4 (14.8)6 (11.1)0.669b
 Triple regimen included basiliximabe4 (14.8)4 (14.8)8 (14.8)1.000b

ICU care, N(%)17 (63.0)9 (33.3)26 (48.1)0.029b
Septic shock, N(%)12 (44.4)5 (18.5)17 (31.5)0.040b
History of IFIs, N(%)3 (11.1)2 (7.4)5 (9.2)1.000b

Invasive fungal infection
 Proven, N(%)10 (37.0)11 (40.7)21 (38.9)0.780b
 Probable, N(%)17 (63.0)16 (59.3)33 (61.1)

Data are the mean ± SD or No. (%)

From the Independent t-test

From the Chi-square test or Fisher’s exact test

Triple regimen; tacrolimus, mycophenolate mofetil plus steroid

Double regimen; tacrolimus plus steroid

Triple regimen included basiliximab; basiliximab, mycophenolate mofetil plus steroid

BMI, body mass index; ICU, intensive care unit

Korean J Clin Pharm 2019;29:89-100 https://doi.org/10.24304/kjcp.2019.29.2.89
© 2019 Korean J Clin Pharm