pISSN 1226-6051
eISSN 2508-786X
eISSN 2508-786X
Comparisons of efficacy in therapeutic drug monitoring (TDM) vs. non-TDM groups
| TDM (n = 27) | non-TDM (n = 27) | Total (n = 54) | ||
|---|---|---|---|---|
| Switching rates to 2nd line antifungal agents, N(%) | 7 (25.9) | 15 (55.6) | 22 (40.7) | 0.027 |
| Total duration of antifungal agents use, days | 166 [32-937] | 93 [16-734] | 126 [16-937] | 0.012 |
| Readmission to hospital for IFIs, N(%) | 10 (37.0) | 13 (48.1) | 23 (42.6) | 0.410 |
| 3-month mortality, N(%) | 2 (7.4) | 4 (14.8) | 6 (11.1) | 0.390 |
| LOS, days | 66 [6-473] | 27 [0-163] | 59 [0-473] | 0.049 |
| ICU LOS, days | 7 [0-149] | 0 [0-163] | 1.5 [0-163] | 0.288 |
| Duration of ventilator, days | 4 [0-177] | 0 [0-152] | 2.5 [0-177] | 0.236 |
Data are the No. (%) or median [min-max]
From the Chi-square test
From the Mann-Whitney U test
IFIs, invasive fungal infections; LOS, hospital length of stay; ICU LOS, intensive care unit length of stay