pISSN 1226-6051
eISSN 2508-786X
eISSN 2508-786X
Comparison of number of prescriptions before and after DUR
| Category of drug | Age (years) | Before DUR (%) | After DUR (%) | |
|---|---|---|---|---|
| Total number of inappropriate prescription (%) | 65-74 | 2,036 (54.8) | 1,895 (49.1) | <0.001 |
| 75-84 | 1,530 (41.2) | 1,732 (44.9) | 0.001 | |
| over 85 | 150(4.0) | 230 (6.0) | <0.001 | |
| total | 3,716 | 3,857 | <0.001 | |
| Tricyclic antidepressants & Long-acting benzodiazepines | ||||
| Amitriptyline | 65-74 | 921 (56.5) | 653 (47.7) | <0.001 |
| 75-84 | 631 (38.7) | 615 (45.0) | 0.001 | |
| over 85 | 77 (4.7) | 100 (7.3) | 0.003 | |
| total | 1,629 (43.8) | 1,368 (35.4) | <0.001 | |
| Clonazepam | 65-74 | 765 (54.1) | 836 (47.6) | <0.001 |
| 75-84 | 604 (42.7) | 824 (46.9) | 0.020 | |
| over 85 | 44 (3.1) | 97 (5.5) | 0.001 | |
| total | 1,413 (38.0) | 1,757 (45.5) | <0.001 | |
| Nortriptyline | 65-74 | 215 (49.8) | 314 (55.1) | 0.095 |
| 75-84 | 194 (44.9) | 228 (40.0) | 0.119 | |
| over 85 | 23 (5.3) | 28 (4.9) | 0.769 | |
| total | 432 (11.6) | 570 (14.7) | <0.001 | |
| Diazepam | 65-74 | 88 (56.0) | 62 (60.2) | 0.569 |
| 75-84 | 67 (42.7) | 37 (35.9) | 0.251 | |
| over 85 | 2 (1.3) | 5 (4.9) | 0.084 | |
| total | 157 (5.2) | 103 (2.6) | 0.000 | |
| Imipramine | 65-74 | 34 (58.6) | 21 (50.0) | 0.526 |
| 75-84 | 21 (36.2) | 21 (50.0) | 0.252 | |
| over 85 | 3 (5.2) | 0 (0.0) | 0.143 | |
| total | 58 (1.5) | 42 (1.0) | 0.046 | |
| Flunitrazepam | 65-74 | 9 (90.0) | 3 (60.0) | 0.171 |
| 75-84 | 1 (10.0) | 2 (40.0) | 0.171 | |
| over 85 | 0 | 0 | - | |
| total | 10 (0.2) | 5 (0.1) | 0.172 | |
| Ethyl loflazepate | 65-74 | 0 | 1 (25.0) | 0.197 |
| 75-84 | 5 (83.3) | 3 (75.0) | 0.747 | |
| over 85 | 1 (16.7) | 0 | 0.389 | |
| total | 6 (0.1) | 4 (0.1) | 0.447 | |
| Clobazam | 65-74 | 1 (33.3) | 2 (66.7) | 0.187 |
| 75-84 | 4 (66.7) | 1 (33.3) | 0.187 | |
| over 85 | 0 | 0 | - | |
| total | 6 (0.1) | 3 (<0.1) | 0.447 | |
| Clomipramine | 65-74 | 2 (50.0) | 3 (60.0) | 0.764 |
| 75-84 | 2 (50.0) | 2 (40.0) | 0.764 | |
| over 85 | 0 | 0 | - | |
| total | 4 (0.1) | 5 (0.1) | 0.781 | |
| Selective serotonin reuptake inhibitor | ||||
| Escitalopram | 65-74 | 659 (58.2) | 819 (55.5) | 0.172 |
| 75-84 | 434 (38.3) | 607 (41.1) | 0.145 | |
| over 85 | 40 (3.5) | 50 (3.4) | 0.843 | |
| Total | 1,133 (30.4) | 1,476 (38.2) | 0.002 | |
| Paroxetine | 65-74 | 231 (60.2) | 326 (54.6) | 0.087 |
| 75-84 | 142 (37.0) | 244 (40.9) | 0.223 | |
| over 85 | 11 (2.9) | 27 (4.5) | 0.189 | |
| total | 384 (10.3) | 597 (15.4) | <0.001 | |
| Sertraline | 65-74 | 117 (54.2) | 140 (54.5) | 0.947 |
| 75-84 | 96 (44.4) | 114 (44.4) | 0.985 | |
| over 85 | 3 (1.4) | 3 (1.2) | 0.830 | |
| total | 216 (5.8) | 257 (6.6) | 0.742 | |
| Fluoxetine | 65-74 | 15 (55.6) | 26 (68.4) | 0.290 |
| 75-84 | 12 (44.4) | 12 (31.6) | 0.290 | |
| over 85 | 0 (0.0) | 0 (0.0) | - | |
| total | 27 (0.7) | 38 (0.9) | 0.430 | |
| Fluvoxamine | 65-74 | 13 (40.6) | 11 (40.7) | 0.993 |
| 75-84 | 18 (56.3) | 11 (40.7) | 0.235 | |
| over 85 | 1 (3.1) | 5 (18.5) | 0.051 | |
| total | 32 (0.8) | 27 (0.7) | 0.228 | |
| Short-acting and intermediate-acting benzodiazepine | ||||
| Lorazepam | 65-74 | 264 (58.1) | 337 (54.0) | 0.176 |
| 75-84 | 183 (40.3) | 267 (42.8) | 0.415 | |
| over 85 | 7 (1.5) | 20 (3.2) | 0.084 | |
| total | 454 (12.2) | 624 (16.1) | 0.004 | |
| Alprazolam | 65-74 | 921 (53.1) | 1,083 (54.2) | 0.471 |
| 75-84 | 730 (42.1) | 820 (41.1) | 0.541 | |
| over 85 | 85 (4.9) | 94 (4.7) | 0.787 | |
| total | 1,736 (46.7) | 1,997 (51.7) | 0.915 | |