pISSN 1226-6051
eISSN 2508-786X

Table. 4.

Table. 4.

The frequency of potential drug interactions

 Potential DDI pairs (n=25,613)n (%)

 Lexi-Interact online risk rating D or Micromedex® risk rating major
Glimepiride (n=19,672)Fluconazole PO/INJc4,207 (16.4%)
Ofloxacin Topical/Othersc3,258 (12.7%)
Levofloxacin PO/INJb,c2,920 (11.4%)
Levofloxacin Topical/Othersb,c2,756 (10.8%)
Ofloxacin PO/INJa2,380 (9.3%)
Ciprofloxacin PO/INJa1,992 (7.8%)
Moxifloxacin Topical/Othersc908 (3.5%)
Isoniazid PO/INJb,c311 (1.2%)
Others940 (3.6%)

Gliclazide (n=2,081)Ofloxacin Topical/Othersc357 (1.4%)
Levofloxacin PO/INJc342 (1.3%)
Levofloxacin Topical/Othersb,c309 (1.2%)
Fluconazole PO/INJb,c302 (1.2%)
Ofloxacin PO/INJc278 (1.1%)
Others493 (1.8%)

  Total22,680 (88.5%)

Lexi-Interact online risk rating C or Micromedex® risk rating moderate

Glimepiride (n=2,789)Clarithromycin PO/INJb,d1,386 (5.4%)
Oxytetracycline Topical/Othersb,d443 (1.7%)
Sulfamethoxazole-trimethoprim PO/INJd389 (1.5%)
Doxycycline PO/INJd365 (1.4%)
Others206 (0.8%)

  Total2,933 (11.5%)

DDI: drug drug interactions, PO/INJ: orally/injection, Others: test strip, inspection kit, etc.

Lexi-Interact online drug interaction risk rating D,

Lexi-Interact online drug interaction risk rating C,

Micromedex® drug interaction risk rating major,

Micromedex® drug interaction risk rating moderate.

Korean J Clin Pharm 2018;28:188-93 https://doi.org/10.24304/kjcp.2018.28.3.188
© 2018 Korean J Clin Pharm