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Medical Utilization and Antibiotics Use of Prostatitis Patients in Korea
Korean J Clin Pharm 2018;28(2):117-123
Published online June 30, 2018
© 2018 Korean College of Clinical Pharmacy.

Boram Lee1, Yoon Jung Choi2*, Younsong Choi2, Nayoung Kong2, and Minsun Choi2

1Graduate School of Public Health, Seoul National University, Seoul 08826, Republic of Korea
2Health Insurance Review and Assessment Service, Seoul 06653, Republic of Korea
Correspondence to: * Yoon jung Choi, Health Insurance Review and Assessment Service, 267 Hyoryeong-ro, Seocho-gu, Seoul 06653, Republic of Korea
Tel: +82-2-705-6941, Fax: +82-2-6710-5748 E-mail:
Received November 8, 2017; Revised March 30, 2018; Accepted April 11, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Prostatitis, one of the most common diseases of the prostate, is a complex disease with various clinical features. This study aims to analyze the utilization and prescribing patterns of antibiotics in Korean patients with prostatitis between 2008 and 2015.
Methods: We used the National Health Insurance Database complied from the Health Insurance Review and Assessment Service (HIRA). The outcomes included the number of claims, number of patients, medical cost, and length of stay for each year. In addition, the prescribing patterns of antibiotics, including fluoroquinolone, and low-dose use of ciprofloxacin and levofloxacin were investigated.
Results: The total number of patients and medical cost increased by 9.5% and 51.7% from 2008 to 2015, respectively. Most prostatitis patients were classified as chronic prostatitis patients. The prescribing proportion of antibiotics for chronic prostatitis outpatients decreased from 71.0% to 66.9% from 2008 to 2015, and fluoroquinolone accounted for more than half of the total antibiotics. Over 80% of prescription of levofloxacin and ciprofloxacin was identified to be for low-dose use.
Conclusion: Most of the patients with prostatitis experienced pain relief and condition improvement after antibiotic treatment; however, chronic prostatitis and chronic pelvic pain syndrome recur easily. Therefore, active disease management and further studies are needed to enhance our understanding of effective treatment for prostatitis.
Keywords : Antibiotics, fluoroquinolone, medical utilization, prostatitis

June 2018, 28 (2)
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