pISSN 1226-6051
eISSN 2508-786X

Table. 5.

Table. 5.

Most common drug-drug interactions described in 13 medication use screening tools

Medication class A Medication class B TIME. 17,20) Beers criteria. 17) ESPIA. 21) Korean 2018. 29) GheOP3S tool. 34) STOPP/START ver2. 37) STOPPJ. 31) Amsterdam tool. 32,39) OPTISCRIPT. 39) RASP 38) Chinese criteria. 25) Czech criteria. 24,41) Taiwan criteria. 24) N
NSAIDs Vitamin K antagonist O O - - O O - - O - - O - 6
ACEI Potassium-sparing diuretics O O O - - O - - - - - O - 5
Beta-blocker CCB O - O - - - - O - - - O - 4
Anticholinergics Anticholinergics O O - - O - - - - - - - - 3
Antiplatelets Vitamin K antagonist - - O - O - - O - - - - - 3
Diuretics NSAIDs - - - - O - - O O - - - - 3
Phenytoin Trimethoprim - O O - O - - - - - - - - 3
Quinolones Theophylline - O O - O - - - - - - - - 3
Trimethoprim Vitamin K antagonist - O O - O - - - - - - - - 3
ACEI ARB - O - - - O - - - - - - - 2
ACEI NSAIDs - - O - - - - - O - - - - 2
AChE inhibitors ARB - - O - - O - - - - - - - 2
Aspirin Antiplatelets - - - - - - - O - O - - - 2
Antiarrythmics Beta-blocker - - - - - - - O - - - O - 2
Bisphosphonate Minerals - - - - O - - O - - - - - 2
Antiarrhythmics Digoxin - - O - - - - O - - - - - 2
CCB Digoxin - - - - O - - O - - - - - 2
ACEI Lithium - O O - - - - - - - - - - 2
Loop diuretics Lithium - O O - - - - - - - - - - 2
NSAIDs RAAS inhibitor - - O - O - - - - - - - - 2
NSAIDs Corticosteroids - O - - O - - - - - - - - 2
NSAIDs Direct thrombin inhibitor O - - - - O - - - - - - - 2
NSAIDs Factor Xa inhibitors O - - - - O - - - - - - - 2
NSAIDs Lithium - - O - O - - - - - - - - 2
NSAIDs SSRI - - - - O - - - O - - - - 2
Benzodiazepines Opioids - O O - - - - - - - - - - 2
ARB Potassium sparing diuretics O - - - - O - - - - - - - 2
Quinolones Vitamin K antagonist - O O - - - - - - - - - - 2

TIME, Turkish inappropriate medication use in the elderly; GheOP3S, The Ghent Older People’s Prescription community Pharmacy Screening; STOPP, Screening Tool of Older Person’s Prescriptions; START, Screening Tool to Alert doctors to Right Treatment; RASP, Rationalization of home medication by an Adjusted STOPP list in older Patients; NSAIDs, Non-Steroidal Anti-Inflammatory Drugs; ACEI, Angiotensin Converting Enzyme Inhibitor; Beta-blocker, Beta adrenergic receptor antagonists; CCB, Calcium Channel Blocker; ARB, Angiotensin Receptor Blocker; AChE, Acetylcholine esterase; RAAS, Renin-Angiotensin Aldosterone System; SSRI, Selective Serotonin Receptor Inhibitor

Korean J Clin Pharm 2021;31:61-78 https://doi.org/10.24304/kjcp.2021.31.1.61
© 2021 Korean J Clin Pharm