pISSN 1226-6051
eISSN 2508-786X
eISSN 2508-786X
Most common drug-drug interactions described in 13 medication use screening tools
| Medication class A | Medication class B | TIME. 17,20) | Beers criteria. 17) | ESPIA. 21) | Korean 2018. 29) | GheOP3S tool. 34) | STOPP/START ver2. 37) | STOPPJ. 31) | Amsterdam tool. 32,39) | OPTISCRIPT. 39) | RASP 38) | Chinese criteria. 25) | Czech criteria. 24,41) | Taiwan criteria. 24) | N |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NSAIDs | Vitamin K antagonist | O | O | - | - | O | O | - | - | O | - | - | O | - | 6 |
| ACEI | Potassium-sparing diuretics | O | O | O | - | - | O | - | - | - | - | - | O | - | 5 |
| Beta-blocker | CCB | O | - | O | - | - | - | - | O | - | - | - | O | - | 4 |
| Anticholinergics | Anticholinergics | O | O | - | - | O | - | - | - | - | - | - | - | - | 3 |
| Antiplatelets | Vitamin K antagonist | - | - | O | - | O | - | - | O | - | - | - | - | - | 3 |
| Diuretics | NSAIDs | - | - | - | - | O | - | - | O | O | - | - | - | - | 3 |
| Phenytoin | Trimethoprim | - | O | O | - | O | - | - | - | - | - | - | - | - | 3 |
| Quinolones | Theophylline | - | O | O | - | O | - | - | - | - | - | - | - | - | 3 |
| Trimethoprim | Vitamin K antagonist | - | O | O | - | O | - | - | - | - | - | - | - | - | 3 |
| ACEI | ARB | - | O | - | - | - | O | - | - | - | - | - | - | - | 2 |
| ACEI | NSAIDs | - | - | O | - | - | - | - | - | O | - | - | - | - | 2 |
| AChE inhibitors | ARB | - | - | O | - | - | O | - | - | - | - | - | - | - | 2 |
| Aspirin | Antiplatelets | - | - | - | - | - | - | - | O | - | O | - | - | - | 2 |
| Antiarrythmics | Beta-blocker | - | - | - | - | - | - | - | O | - | - | - | O | - | 2 |
| Bisphosphonate | Minerals | - | - | - | - | O | - | - | O | - | - | - | - | - | 2 |
| Antiarrhythmics | Digoxin | - | - | O | - | - | - | - | O | - | - | - | - | - | 2 |
| CCB | Digoxin | - | - | - | - | O | - | - | O | - | - | - | - | - | 2 |
| ACEI | Lithium | - | O | O | - | - | - | - | - | - | - | - | - | - | 2 |
| Loop diuretics | Lithium | - | O | O | - | - | - | - | - | - | - | - | - | - | 2 |
| NSAIDs | RAAS inhibitor | - | - | O | - | O | - | - | - | - | - | - | - | - | 2 |
| NSAIDs | Corticosteroids | - | O | - | - | O | - | - | - | - | - | - | - | - | 2 |
| NSAIDs | Direct thrombin inhibitor | O | - | - | - | - | O | - | - | - | - | - | - | - | 2 |
| NSAIDs | Factor Xa inhibitors | O | - | - | - | - | O | - | - | - | - | - | - | - | 2 |
| NSAIDs | Lithium | - | - | O | - | O | - | - | - | - | - | - | - | - | 2 |
| NSAIDs | SSRI | - | - | - | - | O | - | - | - | O | - | - | - | - | 2 |
| Benzodiazepines | Opioids | - | O | O | - | - | - | - | - | - | - | - | - | - | 2 |
| ARB | Potassium sparing diuretics | O | - | - | - | - | O | - | - | - | - | - | - | - | 2 |
| Quinolones | Vitamin K antagonist | - | O | O | - | - | - | - | - | - | - | - | - | - | 2 |
TIME, Turkish inappropriate medication use in the elderly; GheOP3S, The Ghent Older People’s Prescription community Pharmacy Screening; STOPP, Screening Tool of Older Person’s Prescriptions; START, Screening Tool to Alert doctors to Right Treatment; RASP, Rationalization of home medication by an Adjusted STOPP list in older Patients; NSAIDs, Non-Steroidal Anti-Inflammatory Drugs; ACEI, Angiotensin Converting Enzyme Inhibitor; Beta-blocker, Beta adrenergic receptor antagonists; CCB, Calcium Channel Blocker; ARB, Angiotensin Receptor Blocker; AChE, Acetylcholine esterase; RAAS, Renin-Angiotensin Aldosterone System; SSRI, Selective Serotonin Receptor Inhibitor