pISSN 1226-6051
eISSN 2508-786X

Table. 4.

Table. 4.

Comparison of renal function: everolimus with low dose tacrolimus group and conventional dose tacrolimus group

Renal function EVR+Low TAC (n=40) TAC (n=78) p-value
Creatinine mg/dL, mean±SD
Cohort entry date 1.38±0.80 1.08±0.49 0.012*
1 year after cohort entry date 1.37±1.01 1.13±0.55 0.103
eGFR**, mean±SD
Cohort entry date 69.2±34.9 77.9±30.6 0.184
1 year after cohort entry date 72.0±36.5 69.8±24.6 0.701
Δ Renal function***, mean±SD
Creatinine mg/dL -0.42±0.63 0.02±0.44 0.557
eGFR** 7.85±25.5 -6.87±26.0 0.009*

EVR+Low TAC: everolimus+low dose tacrolimus cohort

TAC: conventional dose tacrolimus cohort SD: standard deviation

*
p<0.05

** eGFR by MDRD: estimated glomerular filtrated-modification of diet in renal disease, mL/min/1.73 m2

*** Δ Renal function: renal function of cohort entry date-renal function of 1 year after cohort entry date

Korean J Clin Pharm 2021;31:44-52 https://doi.org/10.24304/kjcp.2021.31.1.44
© 2021 Korean J Clin Pharm