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Table. 4.

Table. 4.

The distribution of severity of drug-drug interaction between drug database and drug-label (N=627)

Database Drug label

Severity N (%) Contraindication N (%) Caution N (%) Others N (%)
95 (15.2) 423 (67.5) 109 (17.4)
Lexicomp®
X 159 (25.4) 47 (29.6) 103 (64.8) 9 (5.7)
D 265 (42.3) 22 (8.3) 188 (70.9) 55 (20.8)
C 131 (20.9) 21 (16.0) 94 (71.8) 16 (12.2)
B 16 (2.6) 0 (0.0) 15 (93.8) 1 (6.3)
No DDI information 48 (7.7) 0 (0.0) 21 (43.8) 27 (56.3)
No drug information 8 (1.3) 5 (62.5) 2 (25.0) 1 (12.5)

Micromedex®
Contraindicated 10 (1.6) 1 (10.0) 9 (90.0) 0 (0.0)
Major 413 (65.9) 77 (18.6) 255 (61.7) 81 (19.6)
Moderate 15 (2.4) 0 (0.0) 11 (73.3) 4 (26.7)
Minor 0 (0.0) 0 - 0 - 0 -
No DDI information 83 (13.2) 7 (8.4) 61 (73.5) 15 (18.1)
No drug information 106 (16.9) 10 (9.4) 87 (82.1) 9 (8.5)

DDI: drug-drug interaction

Korean J Clin Pharm 2020;30:44-50 https://doi.org/10.24304/kjcp.2020.30.1.44
© 2020 Korean J Clin Pharm